Cancer Genetic Testing in Islamabad, Pakistan
Zarqa Genomics Lab (ZGL) offers the latest genetic testing services to support the diagnosis, treatment and management of various cancers. Our comprehensive panels cover a wide range of hereditary and somatic cancer types, helping clinicians offer treatment plans to individual patients.
Whole Exome Sequencing (WES)
Whole Genome Sequencing (WGS)
Next-Generation Sequencing (NGS) panels
Single gene testing
Oncology at ZGL
Oncology overview
Oncology focuses on cancer diagnosis and treatment. ZGL provides advanced genetic testing to support early detection and personalized treatment of cancers. Our genomic technologies analyse complex genetic profiles to identify cancer-related mutations.
How it works
Our genetic tests involve the analysis of DNA to identify mutations, deletions, duplications and other genetic alterations that may increase the risk of developing certain cancers. Using advanced bioinformatics tools, we provide comprehensive reports that include actionable insights for personalized treatment plans.
Common disorders we cover
- Breast cancer
- Lung cancer
- Colorectal cancer
- Prostate cancer
- Stomach (gastric) cancer
- Hepatocellular carcinoma (liver cancer)
- Leukemia
- Lymphoma
- Ovarian cancer
- Bladder cancer
Hereditary cancer syndromes and associated cancers
| Syndrome | Associated cancers |
|---|---|
| BRCA1/BRCA2 mutations | Breast cancer, ovarian cancer, prostate cancer, pancreatic cancer |
| Lynch syndrome (HNPCC) | Colorectal, endometrial, gastric, ovarian, small intestine, ureteral and renal pelvis cancer |
| Li-Fraumeni syndrome | Breast cancer, brain tumors, osteosarcoma, soft tissue sarcomas, leukemia |
| Von Hippel-Lindau syndrome | Renal cell carcinoma, pheochromocytoma, hemangioblastomas, pancreatic neuroendocrine tumors |
| Retinoblastoma | Retinoblastoma, osteosarcoma |
| Familial adenomatous polyposis | Colorectal cancer, desmoid tumors, thyroid cancer, gastric cancer |
| Beckwith-Wiedemann syndrome | Wilms tumor, hepatoblastoma, adrenocortical carcinoma |
| Neurofibromatosis type 1 (NF1) | Neurofibromas, optic gliomas, malignant peripheral nerve sheath tumors |
| Neurofibromatosis type 2 (NF2) | Schwannomas, meningiomas, ependymomas |
| Tuberous sclerosis complex | Renal angiomyolipomas, subependymal giant cell astrocytomas (brain tumors) |
| Peutz-Jeghers syndrome | Gastrointestinal cancers (colorectal, gastric, pancreatic), breast cancer, ovarian cancer |
| Hereditary diffuse gastric cancer | Gastric cancer, lobular breast cancer |
| Multiple endocrine neoplasia type 1 | Parathyroid tumors, pituitary tumors, pancreatic neuroendocrine tumors |
| Multiple endocrine neoplasia type 2 | Medullary thyroid carcinoma, pheochromocytoma, parathyroid adenomas |
| Cowden syndrome | Breast cancer, thyroid cancer, endometrial cancer |
| Hereditary paraganglioma-pheochromocytoma | Paragangliomas, pheochromocytomas |
| Gorlin syndrome | Basal cell carcinoma, medulloblastoma |
Cancer types and associated genes
| Cancer type | Associated genes |
|---|---|
| Breast cancer | BRCA1, BRCA2, TP53, PTEN |
| Ovarian cancer | BRCA1, BRCA2, RAD51C |
| Prostate cancer | BRCA2, HOXB13, PTEN |
| Pancreatic cancer | BRCA1, BRCA2, PALB2 |
| Endometrial cancer | MLH1, MSH2, MSH6, PTEN |
| Uterine cancer | PTEN, MLH1, MSH2 |
| Gastric cancer | CDH1, MLH1, MSH2 |
| Gastrointestinal stromal tumor | KIT, PDGFRA |
| Familial adenomatous polyposis | APC, MUTYH |
| Hereditary paraganglioma/pheochromocytoma | SDHB, SDHD, RET |
| Thyroid cancer | RET, BRAF, NTRK1 |
| Renal cancer | VHL, MET, FLCN |
| Melanoma | CDKN2A, BRAF, NRAS |
| Skin cancer | CDKN2A, BRAF |
| Beckwith-Wiedemann syndrome | CDKN1C, H19, IGF2 |
| Retinoblastoma | RB1 |
| Rothmund-Thomson syndrome (type 2) | RECQL4 |
| Leukemia | RUNX1, TP53, IKZF1 |
| Lymphomas | MYC, BCL2, BCL6 |
| Malignant brain tumors | TP53, PTEN, IDH1 |
| Bone cancer | RB1, TP53, EXT1 |
| Neuroblastoma | ALK, PHOX2B |
| Wilms tumor | WT1, WTX |
| Rhabdomyosarcoma | PAX3, FOXO1 |
ZGL’s commitment to oncology services
We are dedicated to offering precise and advanced genetic testing for oncology. Our commitment to excellence ensures access to the latest genomic techniques, allowing for accurate cancer diagnoses.
Book a cancer genetic test
Visit Zarqa Genomics Lab at First Floor, 44-W, Alay Plaza, Fazal-E-Haq Road, Blue Area, Islamabad, Monday to Saturday, 10:00am to 7:00pm. Call +92 302 5550389 or +92 51 2726866, or email info@zglgenomics.com.
